Nnwale Nucleic Acid Covid-19 Aka Ọhụrụ

N'oge na-adịbeghị anya, Pluslife Biotech, ụlọ ọrụ dabere na Greater Bay Area, weputara ule izizi Covid-19 Nucleic Acid iji nyere aka na mgbochi na njikwa ọrịa.         

Ọrịa COVID-19 kacha ọhụrụ emetụtala Hong Kong n'izu ndị na-adịbeghị anya. Na nzaghachi maka ihe ịma aka gụnyere enweghị ikike maka mgbochi na njikwa ọrịa, yana oke nnwale, gọọmentị Hong Kong ewepụtala mmemme zuru ụwa ọnụ, na-ekesa ngwa nnwale na ikwe ka ndị bi na ha nwalee onwe ha maka COVID-19. Ndị kwesịrị igosipụta nsonaazụ ya nwere ike ịga n'ọdụ nnwale iji nweta nnwale qPCR ọzọ nkwenye.

Usoro nchọpụta nchọpụta na ọgwụgwọ maka COVID-19 (Trial Version 8), nke National Health Commission na National Administration of Traditional Chinese Medicine jikọtara ọnụ, na-ekwu n'ụzọ doro anya na nsonaazụ dị mma nke ule nucleic acid bụ isi ihe nrịba ama maka nchọpụta COVID-19. Tụnyere ule antigen ngwa ngwa, nghọta na nkọwapụta nke nnwale nucleic acid dị elu karịa, ọ nwekwara ike ịchọpụta ndị ọrịa butere ọrịa n'oge mbụ. Agbanyeghị, ule nucleic acid a na-ahụkarị ugbu a dị ka ule qPCR chọrọ ngwa dị oke ọnụ yana usoro ọrụ dị egwu, yabụ a na-eji ule ndị a n'ụlọ ọgwụ, ebe nnwale ndị ọzọ ma ọ bụ ụlọ nyocha. Dị ka nke a, ule qPCR adịghị mma iji nweta nsonaazụ ule ozugbo na saịtị nnwale nke obodo.

Ọ bụ ezie na ule antigen ngwa ngwa dị mfe ma dị mma iji, mmetụta ya dị ala nke ukwuu karịa nke ule qPCR. N'ọtụtụ ọnọdụ, ọ nwere ike ịchọpụta naanị ihe atụ dị mma siri ike, ma ọ bụrụ na ntinye nke nje ndị dị na nlele ahụ eruteghị ọnụ ọgụgụ ụfọdụ, a ga-enwe ike ịme ihe ọjọọ. Ya mere, na mmalite nke ọrịa, ule qPCR ziri ezi karịa ule antigen.

Prọfesọ Zhou SONGYANG, onye guzobere Pluslife Biotech, kwuru, "Site na mgbasawanye ngwa ngwa nke COVID-19 na mkpa na-abawanye maka nyocha COVID-19, na-emepụta ngwaahịa nucleic acid Point of Care Testing (POCT) dabara adaba nke dị ọnụ ala ma dịkwa mma. Nnwale antigen ngwa ngwa, ka ị na-ejigide izi ezi na uche dị ka ule qPCR, ga-aba uru maka ọha mmadụ niile iji chịkwaa ọrịa a nke ọma. "

Pluslife Biotech bụ onye nrụpụta na onye nrụpụta POCT nucleic acid test & ngwaahịa nnwale ụlọ dabere na Mpaghara Greater Bay. Ụlọ ọrụ ahụ ebula ngwa ngwa ngwa ngwa nke mbụ puku puku ngwa nyocha maka ụlọ ọgwụ na ụlọ ọgwụ Hong Kong. Pluslife Biotech bụ ike ọhụrụ n'ọgụ a na-alụso ọrịa a ọgụ na teknụzụ, yana otu n'ime ụlọ ọrụ mbụ na China malitere in vitro diagnostic (IVD) nnwale ụlọ POCT nucleic acid. Pluslife Obere Dock, nke Pluslife Biotech mebere, bụ ngwaahịa nnwale POCT nucleic acid izizi maka COVID-19. Companylọ ọrụ ahụ emechaala sistemụ njikwa ogo ISO13485 yana asambodo CE wee nweta ahịa n'ọtụtụ mpaghara gburugburu ụwa.

Nnwale POCT nucleic acid nke Pluslife ruru ogo nghọta, nkọwapụta na izi ezi, nke yiri ule qPCR. Ọ nwekwara ike ịchọpụta nje n'ụzọ siri ike na LoD dị oke ala (Oke Nchọpụta). LoD kwụsiri ike bụ 200 nnomi/mL, nke ka mma karịa ule qPCR.

Ọzọkwa, Pluslife Mini Dock na-ekwu maka nsogbu ndị dị adị nke ịdabere na ngwa ndị dị oke ọnụ (a na-akwụkarị otu otu ọnụ ahịa karịa ọtụtụ narị puku dollar Hong Kong), ma nwee ike nweta nnwale nucleic acid na saịtị na ọkwa ala wee nweta nsonaazụ ule. ozugbo. N'ihe gbasara usoro nnwale, mgbe ha nwesịrị sample imi imi imi, ndị ọrụ na-etinye naanị swab n'ime lysate na kaadị ule, wee tinye kaadị ule na Mini Dock maka nnwale otu nzọụkwụ wee nweta nsonaazụ.

N'ihe banyere ịrụ ọrụ nnwale, Pluslife Mini Dock nwere ike ịchọpụta ihe nlele dị mma n'ime ihe dị ka nkeji iri na ise wee kwado nlele adịghị mma n'ime nkeji 15, na-ebelata oge echere ma e jiri ya tụnyere ule qPCR (na-abụkarị awa 35-3 na mmịpụta, na-agụnyeghị mbufe nlele. oge na lab). N'ihe gbasara ọnụ ahịa, ọnụ ahịa Pluslife Mini Dock dị ọnụ ala karịa ngwa ule POCT nucleic acid ndị ọzọ dị n'ahịa ahụ, a na-ejikwa ya emegharị ya, na-eme ka ọ dabara maka nnukwu ojiji na ọkwa ahịhịa.

Ọganihu nke ngwaahịa Pluslife Biotech nke nwere mmetụta siri ike, dị ọnụ ala, dị mfe iji yana ntụkwasị obi bụ nke otu ndị nwere ike imeputa ihe siri ike yana itinye uche na teknụzụ.

Prọfesọ Zhou SONGYANG nwere ọtụtụ afọ nke ọkachamara na nyocha na mmepe na ngalaba nke injinịa protein na mpaghara sayensị ndụ ndị ọzọ. O bipụtala ihe karịrị akụkọ 150 dị ka onye edemede mbụ na onye na-ede akwụkwọ kwekọrọ na akwụkwọ akụkọ ụwa ama ama dịka Cell, Nature na Sayensị, yana ngụkọta ihe karịrị ugboro 19,000. Otu R&D nke ụlọ ọrụ na-agụnye ọkwa mbụ nke talent dị elu nke mba ofesi, ndị prọfesọ, PhD na ndị ọkachamara dị elu na ụlọ ọrụ IVD, ndị nwere ahụmịhe dị ukwuu na protein ndị bụ isi, teknụzụ nyocha, usoro ngwaahịa na mmepụta kwụsiri ike.

Ngwaahịa qPCR ọdịnala na-adabere na okpomọkụ dị elu ma nwee ihe ngwaike chọrọ, na-ebute ọnụ ahịa ngwa ngwa n'ozuzu ya; ebe ihe ka ọtụtụ n'ime ule isothermal nucleic acid dị ugbu a nwere ike ilebara okwu ọnụ ahịa anya ma nwee ngwa ngwa mmụba ngwa ngwa, mana ha enweghị ike iru ezigbo uche na nkọwapụta, nke na-eme ka ha ghara inwe ike iji qPCR mee ya ozugbo, yabụ ruo ogologo oge ọ nweghị. Nnwale POCT nucleic acid emebere nke ọma nke enwere ike itinye n'ezinaụlọ yana ụlọọgwụ ahụike obodo.

Iji mepụta ngwaahịa nnwale POCT nucleic acid dị elu, Pluslife Biotech mepụtara RHAM, teknụzụ dị n'okpuru nwere ikike ikike ọgụgụ isi nwere onwe, nke dị iche na teknụzụ nkwalite isothermal ọdịnala dị ka teknụzụ nchọpụta LAMP ma ọ bụ CRISPR.

Teknụzụ RHAM na-egosi arụmọrụ yiri ya dị ka qPCR, yana ọ ka mma karịa teknụzụ nkwalite isothermal ọdịnala (dị ka LAMP) n'ihe gbasara uche, nkwụsi ike na nkọwapụta. The widen ndidi na mma ndakọrịta nke RHAM na-aghọta na otu-nzọụkwụ ọrụ nke sample nhazi, nkwalite na nchọpụta niile-na-otu. Usoro a anaghị agụnye omume dị ka imeghe mkpuchi mgbe nkwalite ahụ gasịrị (enweghị mmetọ ikuku), ma nwee obere ihe achọrọ maka gburugburu mpụga na nkwado ngwaike. Ugbu a, Pluslife Biotech etinyela akwụkwọ maka ikike ikike karịa 60 gburugburu teknụzụ dị iche iche gụnyere RHAM, nke enyerela ọtụtụ n'ime ha.

Ngwaahịa nnwale COVID-19, nke Pluslife Mini Dock nọchitere anya ya, ewepụtala ohere ọnọdụ maka nnwale POCT nucleic acid. Dị ka Prọfesọ Zhou SONGYANG si kwuo, Pluslife Mini Dock nwere ike itinye n'ọnọdụ dị ka omenala, saịtị nnwale ọdụ ụgbọ elu, ihe mberede ụlọ ọgwụ, ule ngwa ngwa tupu oge eruo, ụlọ nyocha ekwentị / ubi / ule na ndị agha, ụlọ ọgwụ obodo, na ọbụna maka nyocha onwe onye. Site na nnwale na-agbanwe agbanwe na saịtị, mgbochi ọrịa na njikwa ọrịa nwere ike nweta na isi mmalite. Enwere ike ịchọpụta ndị ọrịa COVID-19 wee kewapụ ya n'oge, na-ebelata oge nchere maka ndị nwere nsonaazụ adịghị mma.